OED 1.a. Disagreement in character or qualities; want of accordance or harmony; discrepancy, inconsistency.
b. An instance or point of disagreement; a discrepancy, an inconsistency.
2.a. Want of accordance with what is reasonable or fitting; unsuitableness, inappropriateness, absurdity.
b. An instance of such disagreement; an inappropriate matter; an absurdity.
Examples in comedy: (Comic theory page)
fat man's clothes are too tight
skinny man's clothes are too loose
little girl wearing her mother's clothes